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These residues are located at the end of the groove and electrostatically interact with the coactivator backbone, thus forming a charge clamp between the amide nitrogen of F+1 and E897 and the carbonyl group of F+5 and K720 (Figure 3D, middle panel)

Cataract Pathophysiology The lens (often called crystalline lens) is a biconvex, transparent structure in the eye that contributes to light refraction, together with the cornea enabling proper focus on the retina

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