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ABSTRACT Introduction Lipedema is a chronic and progressive disease that predominantly affects women, characterized by a disproportionate increase in subcutaneous adipose tissue (AT), particularly in the lower limbs

It is primarily utilized in in vitro models focused on cellular repair processes and structural matrix research

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This result made us consider the possibility that GC deficiency was likely a consequence of an upstream defect leading to compensatory upregulation of steroidogenic enzyme gene expression
