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Studies conducted on females with PCOS showed alterations in the levels of inflammatory markers, some of the above-mentioned protective enzymes, and antioxidant status compared to females with no ovarian pathology
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Increased levels of indoleacrylic acid (IDA) in the gut microbiota were reported to contribute to its accumulation in the retina, ultimately provoking ferroptosis of RGCs via the AhR/ALDH1A3/FSP1 axis (103)
