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Another study that analyzed data from 164 RLS patients found lower transferrin saturation was correlated with better likelihood of responding to IV iron therapy, especially in women (Park 2020)
This is detrimental not only to sperm health but to other bodily processes that rely on calcium, for example, blood clotting

doi: 10.1007/s00706-005-0335-6

Frameshift and nonsense variants are associated with cardiomyopathy, whereas missense variants are more common in asymptomatic individuals
