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Many clinicians also track outcomes with photos or skin analysis to document before-and-after progress

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The transcriptional profile of the skin microbiota in HL414 was different from other healthy subjects after vitamin B12 supplementation To understand why subject HL414, not others in our healthy cohort, developed acne after vitamin B12 supplementation, we further investigated the specific bacterial transcriptional changes in HL414 compared to the other subjects 14 days after vitamin B12 supplementation