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UK Guidance on Long-Term PPI Use After Bariatric Surgery NICE KTT13 and MHRA guidance recommend using the lowest effective PPI dose for the shortest appropriate duration, with regular review

It is not necessary to withhold vitamin B12 therapy until the precise cause of B12 deficiency is established since absorption studies can be performed at any time

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Effects of Methylcobalamin Injection typically wear off between 48 to 72 hours, though this varies from person to person
