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While this is beneficial for healing, angiogenesis also supports tumor growth and metastasis

According to additional studies in the area where PIN develops, PIN cells can attract macrophages by secreting intercellular adhesion moleculeand CCL2, and these recruited macrophages can stimulate ERK and JNK signals in PIN cells by secreting CXCL1, which stimulates PIN cell proliferation (Fig

Anti-VEGF/VEGFR therapy for cancer: Reassessing the target

Just flip off the plastic cover to expose the rubber stopper
