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NAFLD-associated chronic low-grade inflammation responds to L-carnitine supplementation through reduced hepatic pro-inflammatory cytokines (e.g., IL-6), increased anti-inflammatory cytokine IL-10, and downregulation of key inflammatory pathway components (TLR4, NF-B, JNK) ( NF-B represents a master regulator of inflammatory responses in NAFLD progression

This naturally occurring amino acid helps in fat metabolism in the body

L-Carnitine has demonstrated the ability to promote oxygenation of hearth muscle, support cardiovascular energy, enhance endurance training, and maintain healthy lipid metabolism

10.1038/s41467-020-15136-9 97 KongY.WuM.WanX.SunM.ZhangY.WuZ.et al (2023)