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Additionally, high doses of folic acid (exceeding 0.1 mg per day) may result in hematologic remission in patients with vitamin B12 deficiency

doi: 10.1016/j.jaad.2018.04.047 3 WilliamsKAHuangAHBelzbergMKwatraSG

A recent study involved prevention of microglial/macrophage activation using GW2580 treatment, a microglial activation inhibitor without microglial ablation

The magnitude varies based on lifestyle factors and individual biology
