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Together, these findings demonstrate that, in contrast with acute exposure, chronic disruption of iron homeostasis with consequent GSH depletion remodels cellular redox homeostasis over time, inducing a state we term chronoferroptosis: a persistent ferroptotic adaptation characterized by coordinated alterations in iron-handling and antioxidant defense proteins that may represent early vulnerability to neurodegenerative pathology

Pre-existing Conditions: Patients should discuss with their healthcare provider any history of medical conditions such as epilepsy, migraines, heart, kidney, or liver disease

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Multiple myeloma is an incurable cancer of plasma cells that is predominantly located in the bone marrow