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Specificity of GST-GFP to GSH laden hydrogel homogenates To confirm the specificity of the interaction, nickel-purified GST-GFP was incubated in the presences of homogenates made with equimolar GSH (Figure 3A, top) or cysteine (Figure 3A, bottom)

Physiologically based pharmacokinetic modeling and simulation in pediatric drug development

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The 3D models also predicted that the mutated FGF5 lacked the -12 strands that define the canonical trefoil of the FGF family (Fig
