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GlyT1 is primarily localized in astrocytes surrounding glycinergic and glutamatergic synapses and is widely distributed throughout the CNS

Every time you pause mid-reconstitution to search for a missing item, you increase the window for bacterial exposure and the chance of making an error

Neuron 108 , 608622 (2020)

Identifying a sensory gating deficit in ME/CFS may help to identify the core pathology as the same neuroinflammatory cycle identified in other conditions and better insights (and treatment options) might come from those other conditions that share the same basic pathophysiology but where the pathological process is expressed as a different constellation of symptoms, perhaps due to individual variations in genetic predisposition, developmental stage, environmental stressors and perhaps gender