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Description
Sepsis-induced acute kidney injury (S-AKI) occurs within 7 days of the onset of sepsis, and is extremely common in the intensive care units (ICU), being present in approximately half of the patients with acute kidney injury (AKI) in this environment (2)

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Comprehensive investigations, particularly workup for metabolic, immunemediated, neoplastic, and paraneoplastic disorders, revealed no abnormal findings (Table 1)

Direct preclinical evidence has primarily implicated AKG in the regulation of synaptic plasticity and autophagy-related pathways
