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Authors concluded that, in the process of prostate carcinogenesis, activating histone modifications on GSTP1 are lost and subsequently DNA becomes methylated and inaccessible resulting in transcriptional silencing thus demonstrating interplay between histone reprogramming and promoter region methylation (Okino et al., 2007)
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Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets

Serum melatonin is an alternative index of Parkinsons disease severity
