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These results suggest that sublingual and oral B12 supplementation may serve as viable alternatives to IM injections, particularly in clinical settings where frequent intramuscular administration is impractical or resource intensive

Final Thoughts Although there are no guidelines suggesting the recommended time to take vitamin B12, and there is no clinical evidence showing a link between B12 supplementation at night and sleep disruption, it does have the potential to disrupt sleep

And that brings us back to the central question
