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GO enrichment analysis revealed that the key BP terms were primarily associated with response to xenobiotic stimuli, response to oxidative stress, response to nutrient levels, and the regulation of chemical synaptic transmission

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Additionally, developing novel efficacy endpoints beyond conventional CAP, such as evaluating the specific modulation of hepatic triglyceride compositionparticularly the proportion of lipotoxic saturated fatty acidsmay more directly elucidate the mechanisms underlying its hepatoprotective effects

According to a study by Winther et al., higher concentrations of plasma TMAO were related to mortality, CVDs, and poor renal outcome in patients with type 1 diabetes (137)