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P53-mediated lipoxygenase and iPLA2 pathway As a tumor suppressor, p53 can inhibit tumor cells by arresting the cell cycle, promoting apoptosis and senescence [30, 31]
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doi: 10.1038/s41582-023-00867-2, 12
However, a retrospective study from 2001, using 100 mg zinc per day (as sulphate), found only minor benefits but significant side-effects, with patients on zinc having 7.8 times the risk of getting an infection requiring antibiotics and 12.5 times more likely to experience nausea/vomiting
