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Among the biochemical strategies discovered is the control of the enzyme levels (usually by decreasing their quantities), control of the enzyme catalytic activity (by increasing or decreasing its activity), feedback inhibition of some enzymes (GME and GGP), subcellular compartmentation of AsA, the metabolon assembly of the enzymes, and control of AsA biosynthesis by electron flow

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Self-management domains cover emotions, cognitions, behaviors, sleep, and environment, with strategies like mindfulness, pleasant activities, social support, and behavioral sleep techniques (67, 68, 83)