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Funding This work was supported by the National Natural Science Foundation of China (Grant numbers 82070938, 82371036 and 82401317) and the Program of the Natural Science Foundation of Zhejiang Province (Grant number LTGY23H120003)

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Following a 48-hour treatment with 5-FU or oxaliplatin, 10 l of CCK-8 solution was added to each well and incubated at 37C for 4 h