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Of those who had tumor shrinkage, tumors were completely eradicated in 7% of people treated with nirogacestat, compared with none in the placebo group
In vivo, PNPLA2 is expressed in breast cancer cells and not in normal breast epithelial cells, and PNPLA2 expression is correlated with poor prognosis (211)
5-Amino-1MQ, being a small molecule, has viable oral bioavailability and is often administered in capsule form at 2550 mg/kg
2020;5(7):e364-e365 Marengoni A
