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An increase in total mTOR levels without changes in its phosphorylation status has been previously reported [46]
[1] Cell Line:TRX2 -/- DT40 cells (chicken B-cell line) Concentration:1 mM Incubation Time:30 min pretreatment before 1 g/mL Doxycycline induction Result:Reduced activation of caspase-3 and caspase-9, key markers of mitochondrial apoptosis pathway, compared to untreated cells

This is the same as the relationship between choline and acetylcholine which, as you know, is an essential neurotransmitter in the brain
