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where the liver has become inflamed), fibrosis (with the formation of scar tissue) and finally cirrhosis (permanent damage that can lead to liver failure and cancer)
For example, C-Myc amplified in ovarian cancer cells inhibits ferroptosis by inducing NCOA4-mediated ferritinophagy [94] , but erastin selectively kills iron-addicted ovarian cancer cells by inducing ferroptosis and promoting NCOA4-mediated ferritinophagy and mitochondrial dysfunction [95]
