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The red areas represent negative charges, while blue areas indicate positive charges

However, looking at the results for enzyme expression and activity (Figure 4A,B and Figure 5A,B), it can be seen here that the addition of DMSO results in the production of sulfane sulfur-containing compounds (expression and activity of CTH in serum-free medium increases, Figure 4B and Figure 5B), and there is an increase in the expression level of TST (Figure 4A,B), possibly enabling the activity of this enzyme to be maintained at control levels (no statistically significant change in TST activity, Figure 5A,B)

Only 3 of 350 patients discontinued because of it