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A knockdown study and a small-molecule mouse study are exactly the steps that should precede a human trial, and they are the reason a compound gets taken seriously enough to be studied further
Lv M, Wang C, Li F, Peng J, Wen B, Gong Q, et al
Oxidative medicine and cellular longevity, 2012(1), 324832.
Some patients report improvement with probiotic supplements, though clinical evidence is limited
