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Gene editing technologies that repair mitochondrial function or stem cell therapies aimed at repairing myocardial damage could offer innovative solutions in the future

75 Conversely, forced overexpression of CDO1 in breast cancer cells shifted the flux from glutathione synthesis towards cysteine catabolism, consequently increasing ROS levels and leading to reduced cell viability and growth

ZIP14 contains two mutually exclusive exons, 4 A and 4B, and the ratio of exon 4 A/4B was significantly reduced in adenomas and cancers, which may be used as a tumor marker for identifying CRC and precancerous lesions

doi: 10.1038/nrd4002