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This deficiency restricts tissue uptake, leading to decreased accumulation in the heart and skeletal muscle and potentiates increased renal carnitine loss [21, 22] leading to systemic carnitine depletion [23]
[182] [183] [184] [185] The human serotonin transporter and norepinephrine transporter do not contain zinc binding sites
Other tissues, such as the myocardium and skeletal muscle, have no or very low BBD activity and are highly dependent on the uptake of carnitine from the blood [160]
Aside from that, it also decreases the individual's craving for food which allows them to stick with their dietary plans
