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doi: 10.1016/S0300-9572(98)00128-2

The effect of lutein on genes linked to survival and proliferation in using cell line model-prostate cancer [prostate cancer cell line (PC-3)] cells revealed lutein-induced inhibition of PC-3 cell proliferation in vitro, and this inhibition was enhanced by PPAR agonists and other chemotherapeutic drugs

While this complexity is a defining feature of CHMs holistic approach to treatment, it also necessitates advanced research methodologies to elucidate the complex interactions between CHM components and the biological systems with which they interact

Exp Neurol 203(2):51220, PMID: 17049515 Shen H, Liu Z (2006) JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species