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However, the inhibition of VLDL uptake in mice overexpressing human apoC1 was also observed in the context of LDL-R deficiency, suggesting that apoC1 inhibition of VLDL uptake involves another pathway than LDL-R, probably LRP [65]

In such cases, more aggressive therapy with statins (if tolerable) or nonstatin agents like PCSK9 inhibitors would be warranted

Retrieved November 18, 2015
experts therefore recommend using such products only when the potential maternal benefit clearly outweighs theoretical risk and under obstetric supervision
