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Secretagogues like tesamorelin and ipamorelin produce only receptor adaptation, not suppression, so endogenous function resumes within 48 weeks after a proper taper

Conditions such as: Plantar fasciitis / fasciosis Achilles tendinopathy Chronic ankle sprains Non-healing wounds are notoriously difficult to treat because these tissues have poor blood supply and limited capacity to repair themselves

While these medications effectively decrease acid levels, they fail to address the underlying mechanical dysfunction allowing reflux to occur

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