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However, the efficacy was insufficient for drug registration

Sequence analysis reveals many CarH-like homologues form considerably more complex protein architectures, with the B 12 -binding domain fused to additional enzyme or chromophore-binding domains 12

Contact your healthcare provider promptly if you experience persistent or worsening pain at the injection site that does not resolve within a few hours, spreading redness or warmth extending beyond the immediate injection area, drainage or abscess formation, fever or systemic symptoms accompanying injection site reactions, or hardened nodules or lumps that persist for more than a few days