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BDNF-related peptides Brain-derived neurotrophic factor peptides support neural plasticity and nerve cell survival

Key cautions to keep in view Research status and evidence limits: Much of the mechanistic work is preclinical, and human data are limited

The AUC was estimated over the interval of 090 min (Table 4), which corresponds to the duration of effect seen in clinical trials but may affect the interpretation of the results

Specifically, these analyses replicated prior results showing that daytime self-reported body temperature was associated with greater depressive symptoms 19,20 and build on one prior study showing that the asleepawake body temperature difference was more than twice as large among controls relative to individuals with depression 21