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This uptake was evidenced by the accumulation of the fluorescent dye within the cellular compartments, leading to a notably enhanced green fluorescence intensity compared to the untreated control samples

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Subsequently, Cys and Glu are conjugated by -glutamylcysteine synthetase (-GCS) to form -glutamylcysteine (-GC), which is finally combined with glycine by glutathione synthetase (GS) to produce GSH ( Accumulating evidence has uncovered two additional parallel pathways that act as critical regulators of ferroptosis

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