inhibition of schistosoma mansoni thioredoxin-glutathione reductase by auranofin RCSB PDB - 3H4K: Crystal

With this approach we routinely quantify ~7000 phosphopeptides in just 15 min of LC-MS/MS analysis time with the fast 28 Hz higher-energy collisional dissociation (HCD) 10 scanning method on a Q Exactive HF-X mass spectrometer 8 with overall MS/MS identification rates of more than 50%

This is the most significant limitation No statistical significance testing: The paper does not report p-values or statistical tests

Expression of system x c activity by transfection with cDNAs for xCT and 4F2hc made A2780 cells more resistant to CDDP

Accordingly, these principles have been therapeutically exploited in nanomedicine platforms designed to induce GSH-dependent ROS amplification (Fig