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Description
Its principal components are inter-endothelial tight junction proteins which seal the paracellular space and both luminal and abluminal proteins controlling trans-endothelial movement of carbohydrates, hormones, ions and metabolic by-products 10

There is a case for use of non-steroidal anti-inflammatory drugs for AD as many of these have anti-biofilm and antimicrobial effects, although the clinical data is conflicting (Rivers-Auty et al., 2020)

If undissolved particles remain after 20-30 minutes of patient effort, the peptide may have been damaged during shipping or storage

Annu Rev Physiol 81:235259