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Description
We used to think that B12 was completely safe

Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and pyridoxine concentrations

This is the reason that many B12 supplements (whether they are in a pill form or even a tincture taken sublingually) often have 16,000%+ of your daily recommended intake of B12 in a single serving

However, these body composition hypotheses are based on cell culture and animal data
