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It also depends on how well the person responds to treatment and their overall health

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AOD-9604 appears to reproduce a portion of growth hormones lipolytic signaling in fat tissue increasing lipolytic sensitivity, raising fat oxidation, and restoring suppressed 3-AR expression toward normal in obese animals without engaging the growth-hormone receptor in the classical high-affinity way and without raising IGF-1

A 2021 Nature Communications study then showed that MOTS-c is induced by exercise and that treating mice, including animals started late in life, boosted running capacity and physical performance across young, middle-aged, and old groups [3]