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Another advance was the cloning of the intercellular proteins such as zonulins, claudins, occludins, tricellulins, and the many other protein components that comprise the tight junctions, facilitating the understanding of their contributions toward junctional structure and paracellular permeability [33, 38]
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The time needed for hematological and neurological symptoms to recover after starting vitamin B12 treatment varies among subjects [14,88], but high-quality follow-up studies are not available
