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10.1176/appi.ajp.2007.06091515 45 SharmaS.BlackS
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209 Importantly, GLP-1 functionality is mediated both by factors influencing its production, such as prebiotics and bile acid chelators, 210,211 as well as compounds that prolong its half-life, such as dipeptidyl peptidase-4 (DPP4) inhibitors
Elevated concentrations of GABA in the cerebrospinal fluid of women with PCOS, GABA seems to exert an excitatory effect on GnRH neurons and this leads to greater secretion of LH by the pituitary gland, as occurs in PCOS [18, 19]
