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Lysosomal translocation and activation of mTORC1 are stimulated by increased glutaminolysis or an analog of cell KG

131 The production of RONS increases the sensitivity of cells to genotoxic drugs by decreasing the activity of DNA-PKcs, hindering repair processes, and leading to the accumulation of DSBs

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Abstract Alpha-momorcharin (-MC), a type I ribosome-inactivating protein (RIP) isolated from Momordica charantia seeds, has been extensively studied for its antitumor, antiviral and antifungal activities
