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Peter Marks, director of the FDA's Center for Biologics Evaluation and Research, said in a statement

Mechanism of action of GLP1-RAs GLP-1 is a peptide, an incretin hormone that is continuously secreted by the enteroendocrine L cells of the small intestine

Watch for signs like right upper abdominal pain, jaundice (yellowing of the skin or eyes), fever, or nausea that may indicate gall bladder problems while taking semaglutide

The placebo effect is also very real, especially with pain
