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It works systemically, meaning it does not need to be injected near the injury site to be effective
The caloric deficit also means reduced protein availability for tissue synthesis, reduced micronutrient availability, and potentially reduced copper delivery to the enzymatic systems that GHK-Cus carrier function bypasses

Enhancing the stability of SLC7A11 can inhibit ferroptosis, while the destabilization of SLC7A11 can increase the sensitivity to ferroptosis (Liu et al., 2019)
