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Furthermore, the delivery mechanisms of CRISPR systems can stimulate immunological responses and affect neural cells

The basic neurological assessment comprises the general medical and neurological history, inspection of the feet, and neurological examination of sensation using simple semi-quantitative bed-side instruments such as the 10g Semmes-Weinstein monofilament or Neuropen 74 ( to assess touch/pressure), NeuroQuick 75 or Tiptherm 76 (temperature), calibrated Rydel-Seiffer tuning fork (vibration), pin-prick (pain), and tendon reflexes (knee and ankle)

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