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In recent years, extensive research (Figure 2) has shown that TMAO can activate the inflammasome NOD-like receptor protein 3 (Nlrp3) through different pathways to activate the inflammatory signal pathway, resulting in aggravation of oxidative stress and, in turn, of endothelial dysfunction

RNAi Worms were exposed to gene-specific dsRNA by feeding as described [117]

These microbial changes are correlated with fluctuations in beta diversity, which represent structural changes in the microbial community, although alpha diversity is frequently stable
