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Description
Whilst TAGs and phospholipids are metabolized, the cholesterol is then either exported through ATP-binding cassette transporters, or esterified and accumulates as droplets, which leads to the formation of foamy macrophages (110)

This protective layer shields it from being broken down during digestion, allowing it to be absorbed far more effectively

doi: 10.1093/cid/ciab546 11 BedogniG.GastaldelliA.MancoM.De ColA.AgostiF.TiribelliC.et al

Both RickA and Sca2 contribute to cell-to-cell spread, however Sca2-based motility is the major mediator of cell-to-cell spread 34,35,36,37,64
