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Variola proteins that may be hindered include those involved in viral replication, specifically, encoded viral DNA topoisomerases, and evasion of host immunologic defenses

Science 179 , 588590 (1973)

Overexpressing FSP1 in cells lacking GPX4 expression was shown to significantly reduce specific phospholipid peroxidation products compared to control cells [15, 16]

drug toxicity and adverse effects , which discusses mechanisms for adverse effects produced both during normal drug therapy and after an overdose, Drug toxicity and adverse effects There is no consistent use of terminology in describing effects of drugs that were not intended when the drug was prescribed