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If a deficiency does not exist, supplementing Vitamin B12 will likely not have the same positive effect. B12 injections are available, for $15 to $50 a pop, at spas and wellness centers, but its smart to talk to your physician before you spend money on them

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This happens because certain MTHFR mutations (C667T and A129C) lower the amount of active folate being produced in the body, and the use of vitamin B12 requires the active form of folate