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These findings provide another mechanism for Mn-induced dysfunction of dopamine neurons rather than the direct loss of these neurons

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Inhibition of oxidative stress Oxidative stress is believed to be one of the underlying causes of cellular dysfunction and death in PD

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10.1126/science.887941 34 KhairovaR

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Overall, the role of arginine metabolism in pulmonary fibrosis is highly context-dependent, influenced by the interplay between the arginase and NOS pathways and the regulatory control of enzymes such as DDAH and ASS1

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