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The [2Fe2S]-bridged dimer is enzymatically inactive but oxidative stress, increased GSSG concentrations or reduced availability of GSH for the [FeS] complex coordination, results in degradation of the cluster and formation of enzymatically active Grx2 monomers

Testosterone, as one of the androgens, can be reduced to dihydrotestosterone (DHT) by 5-reductase (SRD5A) enzyme, which has three isotypes

Autophagy was also ineffective in BRAF inhibitor resistant melanoma cells due to attenuated level of autophagy associated proteins [150]

iPSC-derived human liver organoid culture The iHLOs at various developmental stages were obtained from 3Dnamics, Inc
