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Since Graves disease (GD) is an autoimmune disease caused by antibodies, a possible disease-modifying approach researchers are examining is to target a receptor that would potentially lead to antibody reduction
10.1016/j.cellimm.2018.01.020 [DOI] [PMC free article] [PubMed] [Google Scholar] 66

Long-term efficacy of vedolizumab for ulcerative colitis
Key pathways such as PI3K-AKT-mTOR, LKB1-AMPK, E-cadherin-Hippo-YAP/TAZ, and VHL-HIF critically modulate ferroptosis in cancers via metabolic regulation and stress-response mechanisms ( In the future, integrating strategies to target ferroptosis defense pathways and enhance the efficacy of cancer immunotherapy will represent a promising therapeutic approach
