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Several signaling pathways in the pathology of AD such as amyloid plaque cleavage, metal ion hypothesis, amyloid degradation, initiation of amyloidogenic and non-amyloidogenic pathway, oxidative stress hypothesis, metabolic syndrome, insulin resistance and tau phosphorylation associated, apolipoprotein (APOE)-cholesterol, neurofibrillary tangles (NFTs) accumulation and Insulin resistance prove to be beneficial in order to find the definite target for treatment of AD
Assessment of progression of pulmonary fibrosis based on metabonomics and analysis of intestinal microbiota

Frequent coexpression of MRP/GS-X pump and -glutamylcysteine synthetase mRNA in drug-resistant cells, untreated tumor cells, and normal mouse tissues
